Anthropic’s life sciences R&D plugin: search papers, compounds, targets and trials, and run single-cell QC and nf-core pipelines.
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About
Anthropic's bio-research plugin, one of its knowledge-work plugins, for early-stage life sciences R&D. It's built for Cowork, Anthropic's desktop agent, and also works in Claude Code. It bundles connectors to literature, compound, drug-target and clinical-trial databases, and skills for single-cell analysis, sequencing pipelines, lab data conversion and choosing which research problem to work on. What you can do with it - Search the literature in PubMed, bioRxiv and medRxiv preprints, and Consensus - Look up bioactive compounds in ChEMBL, find and prioritise drug targets with Open Targets, and review studies on ClinicalTrials.gov - Run quality control on single-cell RNA-seq data (.h5ad, or 10x Genomics .h5) following scverse best practices, with MAD-based filtering and plots - Integrate and batch-correct single-cell data, transfer cell-type labels and analyse multi-modal data with scvi-tools models such as scVI, scANVI, totalVI, PeakVI and MultiVI - Run nf-core pipelines (rnaseq, sarek for variant calling, atacseq) on your own FASTQ files or public GEO/SRA data, from the samplesheet to checking the outputs - Convert instrument exports (PDF, CSV, Excel, text) from cell counters, plate readers, spectrophotometers, qPCR and chromatography systems into Allotrope Simple Model JSON or a flat CSV, with parser code to hand to data engineers - Pitch a new project idea, troubleshoot a stuck one or think through a strategic decision with a problem-selection framework based on Fischbach and Walsh's paper in Cell - Make scientific figures in BioRender Connectors it bundles - No account needed: PubMed, bioRxiv (with medRxiv), ClinicalTrials.gov, ChEMBL and Open Targets - Sign in with your own account: Consensus, BioRender, Synapse (Sage Bionetworks), Wiley Scholar Gateway and Owkin - Benchling is listed too, but its address is still a placeholder, so it doesn't connect yet - Optional extras you download yourself: 10x Genomics' txg-mcp and Harvard MIMS's ToolUniverse Its skills are written for categories rather than products, so another server of the same kind works in place of a bundled one. How to install it In Claude Code, run claude plugin marketplace add anthropics/knowledge-work-plugins, then claude plugin install bio-research@knowledge-work-plugins. Its start skill checks which connectors are working and lists the analysis skills. Good to know - The nf-core pipelines need Docker, Nextflow and Java on your machine; the skill checks your environment and runs a test profile before the real run. - The single-cell, scvi-tools and Allotrope skills run bundled Python scripts, so they need Python with packages such as scanpy, scvi-tools and allotropy. - Anthropic presents the Allotrope converter as an example skill, to adapt to your own schemas. - The skills are Apache 2.0. Each connector is run by its own provider, under its own terms.
Once it’s added
“Search PubMed for recent papers on KRAS G12C inhibitor resistance”
“Run QC on my single-cell data in sample.h5ad”
“Set up an RNA-seq pipeline for GSE110004”
“Search ChEMBL for compounds targeting EGFR”
Before you add it
Reads only
Papers and preprints in PubMed, bioRxiv and medRxiv · Compounds and bioactivity in ChEMBL, and targets in Open Targets · Studies on ClinicalTrials.gov · Your sequencing, single-cell and instrument files, and public GEO/SRA data
Makes changes · your agent can ask first
QC-filtered single-cell files, plots and pipeline outputs on your machine · Allotrope JSON, flat CSVs and parser code from instrument exports · Figures in BioRender, when you connect it
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Runs on your machine.
/plugin marketplace add anthropics/knowledge-work-plugins /plugin install bio-research@knowledge-work-plugins
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Plugins people install alongside Bio Research.
“Find drug targets for idiopathic pulmonary fibrosis”
“Help me evaluate a new project idea”
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Plugins people install alongside Bio Research.
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A community MCP server for Zotero: your agent searches, reads, annotates and adds papers to your research library, locally or on the web.
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Safe to install in every agent it supports. Claude plugins.
